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Digital Twins: Applications to the Design and Optimization of Bioprocesses

Digital Twins: Applications to the Design and Optimization of Bioprocesses

Paperback

Series: Advances in Biochemical Engineering & Biotechnology (Hardcover), Book 177

Medical ReferenceTechnology & Engineering

ISBN10: 3030716589
ISBN13: 9783030716585
Publisher: Springer Nature
Published: Apr 27 2022
Pages: 254
Weight: 0.82
Height: 0.55 Width: 6.14 Depth: 9.21
Language: English

Potential of model-based design of experiments approaches for bioprocess scale-down.- Digital Twins and Their Role in Model-Assisted Design of Experiments.- Digital twins for bioprocess control strategy development and realization.- The Kalman filter for the supervision of cultivation processes.-The challenge of implementing digital twins in operating value chains.- Digital twins in the (bio)pharma industry.- Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells.- Euler-Lagrangian Simulations: A Proper Tool for Predicting Cellular Performance in Industrial Scale Bioreactors.

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Herwig, Christoph

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Technology & Engineering