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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Immunohistochemical evaluation of VEGF-C and COX-2 in PTC

Immunohistochemical evaluation of VEGF-C and COX-2 in PTC

Steger de Oliveira Costa Pires, Janaina
Saddi, Vera

Paperback

Genetics

ISBN10: 6209211453
ISBN13: 9786209211454
Publisher: Our Knowledge Publishing
Published: Nov 7 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Thyroid cancer is the most common malignant neoplasm of the endocrine system. Although it is a relatively rare pathology, accounting for approximately 1% of new cases of malignant diseases, a trend toward increased incidence has been recognized in various parts of the world. This study analyzed the expression of COX-2 and VEGF-C in patients diagnosed with papillary thyroid carcinoma (PTC) in Goiânia, as well as the possible associations between the expression of these markers and the following factors: lymph node metastasis, distant metastasis, tumor size, age, extravasation/invasion of adjacent tissues, and gender. A total of 165 patients with a confirmed histopathological diagnosis of PTC were evaluated. The results of this study corroborate other studies that have demonstrated the usefulness of COX-2 and VEGF-C proteins in identifying PTC patients at higher risk of disease progression due to their association with the presence of regional lymph node metastases and invasion of adjacent tissue.

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Genetics

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