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Physics at the Biomolecular Interface: Fundamentals for Molecular Targeted Therapy
Hardcover
Series: Soft and Biological Matter
Medical ReferenceBiologyChemistry
ISBN13: 9783319308517
Publisher: Springer Nature
Published: Jul 22 2016
Pages: 483
Weight: 1.93
Height: 1.06 Width: 6.14 Depth: 9.21
Language: English
This book focuses primarily on the role of interfacial forces in understanding biological phenomena at the molecular scale. By providing a suitable statistical mechanical apparatus to handle the biomolecular interface, the book becomes uniquely positioned to address core problems in molecular biophysics. It highlights the importance of interfacial tension in delineating a solution to the protein folding problem, in unravelling the physico-chemical basis of enzyme catalysis and protein associations, and in rationally designing molecular targeted therapies. Thus grounded in fundamental science, the book develops a powerful technological platform for drug discovery, while it is set to inspire scientists at any level in their careers determined to address the major challenges in molecular biophysics.
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