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Podatnośc i odpornośc na zakażenie wirusem HIV
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ISBN10: 6209010180
ISBN13: 9786209010187
Publisher: Wydawnictwo Nasza Wiedza
Published: Aug 22 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: Polish
ISBN13: 9786209010187
Publisher: Wydawnictwo Nasza Wiedza
Published: Aug 22 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: Polish
W niniejszym badaniu przeprowadziliśmy analizę porównawczą częstości występowania niektórych polimorfizmów w genach związanych z zakażeniem wirusem HIV w trzech różnych grupach etnicznych w Brazylii oraz w grupie osób zakażonych wirusem HIV-1. Zgodnie z oczekiwaniami, analizowane allele nie występowaly z podobną częstotliwością w badanych grupach etnicznych w Brazylii. Obserwowane częstotliwości alleli nie różnily się statystycznie w porównaniu z osobami zakażonymi i niezakażonymi HIV-1. Jednak po podziale osób zakażonych na podgrupy stwierdziliśmy różne częstotliwości alleli genów, co sugeruje, że analizowane mutacje mogą byc odpowiedzialne za opóźnienie progresji AIDS. Wplyw polimorfizmu niektórych alleli na progresję AIDS pozostaje nadal kontrowersyjny. W niniejszej pracy wykazaliśmy, że niektóre polimorfizmy występowaly we wszystkich badanych grupach etnicznych. Badanie to bylo pionierskie w Brazylii i dlatego ma ogromne znaczenie dla lepszego poznania genetyki populacji brazylijskiej, a także wplywu różnych polimorfizmów w genach gospodarza na progresję AIDS.
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