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Attività neuroprotettiva della quercetina
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ISBN10: 6202366117
ISBN13: 9786202366113
Publisher: Edizioni Sapienza
Published: Aug 8 2025
Pages: 280
Weight: 0.83
Height: 0.63 Width: 6.00 Depth: 9.00
Language: Italian
ISBN13: 9786202366113
Publisher: Edizioni Sapienza
Published: Aug 8 2025
Pages: 280
Weight: 0.83
Height: 0.63 Width: 6.00 Depth: 9.00
Language: Italian
La fluorosi è diventata un problema sanitario endemico in tutto il mondo. La fluorosi è un problema importante che incide pesantemente sulla qualità della vita di milioni di persone e che, in ultima analisi, causa diversi disturbi metabolici e degenerativi. Questo libro tratta la neurodegenerazione, la neuroregenerazione e la neuroprotezione. L'esposizione prolungata al fluoruro di sodio negli organismi porta a deficit di apprendimento e di memoria dovuti alla diminuzione dei recettori nicotinici dell'acetilcolina e alla neurodegenerazione. I motivi principali di questi cambiamenti sono dovuti allo stress ossidativo e ai danni indotti dall'eccitotossicità nel cervello in via di sviluppo. Il documento illustra la neurotossicità del fluoruro di sodio e il ruolo migliorativo della quercetina. La quercetina è il principale flavonoide della dieta umana. L'obiettivo principale di questo libro è quello di valutare il ruolo protettivo della quercetina contro la neurodegenerazione indotta dal fluoruro di sodio con gli opportuni marcatori di stress ossidativo, i neurotrasmettitori, i parametri istologici, fisici e comportamentali corrispondenti alla corteccia cerebrale e all'ippocampo del cervello in via di sviluppo del ratto. In questo libro, la quercetina viene evidenziata come un trattamento potenzialmente efficace per le malattie neurodegenerative.
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