Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Dose-Exposure-Response Modeling: Methods and Practical Implementation

Dose-Exposure-Response Modeling: Methods and Practical Implementation

Wang, Jixian

Hardcover

Series: Chapman & Hall/CRC Biostatistics

Medical ReferenceProbability & Statistics

ISBN10: 1032596252
ISBN13: 9781032596259
Publisher: CRC Press
Published: Feb 18 2026
Pages: 346
Weight: 1.50
Height: 0.81 Width: 6.14 Depth: 9.21
Language: English

This thoroughly revised and updated new edition reflects the progress that has been made in dose-exposure-response (DER) modeling. As the title suggests, the new edition covers more topics on dose and dose adjustment. A large part of the book has been rewritten, including an updated Bayesian analysis and modeling chapter with new materials on ap-proximate Bayesian modeling with misspecified models, Bayesian bootstrap for the cut-the-feedback approach, and meta-regression with Stan codes for implementation. Two new chapters in this edition include one on causal DER modeling, with an introduction to the concept of causal DER relationship, approaches such as the generalized propensity score and instrumental/control function approaches for adjustment for observed and un-observed confounders, and Bayesian causal DER modeling. Another new chapter is dedicated to learning DER relationships with the concept and methods of machine learning, including applications to adaptive dose finding trials by bandits, contextual bandits, and Thompson sampling with Bayesian bootstrap, adaptive control for tracking using a dynamic model with an application for individual warfarin dosing. The new appendix contains non-standard materials used in the book.

Also in

Probability & Statistics

View All