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Corynebacterium Glutamicum: Biology and Biotechnology
Hardcover
Series: Microbiology Monographs, Book 23
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ISBN13: 9783642298561
Publisher: Springer
Published: Aug 14 2012
Pages: 416
Weight: 1.63
Height: 1.08 Width: 6.34 Depth: 9.46
Language: English
Corynebacterium glutamicum was discovered in Japan in 1956 as a natural glutamate producer. Its microbial factory qualities, such as its physiological plasticity and robust catalytic functionalities, have since facilitated the development of efficient production processes for amino acids, nucleotides and vitamins.
This monograph illustrates how the information gleaned from complete genome sequencing allows the rational engineering of the entire cellular metabolism and how systems biology permits the further optimization of C. glutamicum as a biocatalyst. Aspects of gene regulation, metabolic pathways, sugar uptake, protein secretion, cell division and biorefinery applications highlight the enormous biotechnological and biorefinery potential.
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