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Bactéries résistantes aux antibiotiques dans les eaux usées
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ISBN10: 6208674204
ISBN13: 9786208674205
Publisher: Editions Notre Savoir
Published: Feb 24 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: French
ISBN13: 9786208674205
Publisher: Editions Notre Savoir
Published: Feb 24 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: French
Les carbapénèmes (antibiotiques bêta-lactamines) jouent un rôle central contre les infections bactériennes et servent d'antibiotiques de réserve. Les Enterobacteriaceae, qui peuvent développer une résistance aux carbapénèmes par le biais de carbapénémases, sont présentes dans le système digestif humain et animal et peuvent également se retrouver dans les eaux usées. C'est pourquoi l'épidémiologie basée sur les eaux usées offre une bonne possibilité de screening de la résistance aux antibiotiques. L'objectif de ce travail était de détecter les entérobactéries résistantes aux carbapénèmes et leurs mécanismes de résistance dans les eaux usées de Graz. Les eaux usées non traitées et traitées ont été analysées sur des plaques MacConkey et Chromagar. Les colonies ont été identifiées par MALDI-TOF-MS, des antibiogrammes ont été établis selon les critères EUCAST et les carbapénèmases ont été séquencées. 31 isolats étaient porteurs du gène rare KPC-2, non seulement chez Klebsiella pneumoniae, mais aussi chez Enterobacter spp. Les souches productrices de KPC-2 ont généralement montré une résistance aux carbapénèmes et au céfépime. De plus, un isolat de GES-5 a été détecté pour la première fois en Autriche.
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