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Deteção fenotÃpica e genotÃpica de MDR de P aeruginosa e B cepecia
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ISBN10: 6207702271
ISBN13: 9786207702275
Publisher: Edicoes Nosso Conhecimento
Published: Jun 24 2024
Pages: 140
Weight: 0.47
Height: 0.33 Width: 6.00 Depth: 9.00
Language: Portuguese
ISBN13: 9786207702275
Publisher: Edicoes Nosso Conhecimento
Published: Jun 24 2024
Pages: 140
Weight: 0.47
Height: 0.33 Width: 6.00 Depth: 9.00
Language: Portuguese
O objetivo do estudo é isolar e identificar bactérias aeróbias de úlceras do pé diabético em doentes diabéticos e investigar a resistência das bactérias a agentes antibióticos. A P. aeruginosa apresentou nÃveis variados de resistência a: ceftriaxona, cefoxitina e cefepima com uma percentagem de (100%); tobramicina, ciproflaxina e levofloxacina com uma percentagem de (41.1%); ticarclina com ácido clavulânico, piperaclina, ceftazidima e amicacina com uma percentagem de (35,2%); aztreonam com uma percentagem de (47,5); meropenem e imipenem com uma percentagem de (23,5%). Os isolados de B. cepacia mostraram um elevado nÃvel de resistência a todas as classes de antibióticos β-lactâmicos, que incluÃram: ceftriaxona, cefoxitina e cefepima, com uma percentagem de (100%); ticarclina com ácido clavulânico, piperaclina, ceftazidima, tobramicina, ciproflaxina e levofloxacina, com uma percentagem de (87.5%); aztreonam e amicacina com uma percentagem de (62,5%); meropenem, imipenem e gentiamicina com uma percentagem de (37,5%). Os isolados de P. aerginosa apresentavam o gene blaOXA (47,1%) e (58,8%) dos isolados eram portadores do gene blaCTX-M. Todos os isolados de P. aeruginosa apresentaram resultados negativos para os genes blaIMP e blaKPC e a análise por PCR mostrou que o gene integrão era (94,1%).
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