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Staphylococcus epidermidis und Biofilm
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ISBN10: 6209565646
ISBN13: 9786209565649
Publisher: Verlag Unser Wissen
Published: Jan 23 2026
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: German
ISBN13: 9786209565649
Publisher: Verlag Unser Wissen
Published: Jan 23 2026
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: German
Dieses Dokument ist eine umfassende Studie über das Problem der nosokomialen Infektionen im Zusammenhang mit zentralen Venenkathetern, die hauptsächlich durch den Biofilm von Staphylococcus epidermidis verursacht werden. Seine gro e Gefährlichkeit rührt von seiner Fähigkeit her, einen Biofilm zu bilden, eine strukturierte Bakteriengemeinschaft, die in einer schützenden Matrix eingekapselt ist. Dieser Biofilm verleiht den Bakterien eine au ergewöhnliche Toleranz gegenüber Antibiotika und ermöglicht es ihnen, sich der Abwehr des Immunsystems zu entziehen, wodurch Infektionen sehr schwer zu behandeln sind. Das Buch erläutert die komplexen molekularen Mechanismen, die die Bildung dieses Biofilms steuern, insbesondere die Schlüsselrolle des ica-Operons und des Polysaccharids. Angesichts dieser gro en klinischen Herausforderung werden auch die verschiedenen Bekämpfungsstrategien (imprägnierte Katheter, Hemmung der bakteriellen Kommunikation, Enzyme) besprochen und die experimentellen Modelle, sowohl in vitro als auch in vivo, beschrieben, die zur Untersuchung dieses Biofilms und zur Erprobung neuer therapeutischer Lösungen verwendet werden.
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