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Infection, Immune Homeostasis and Immune Privilege

Infection, Immune Homeostasis and Immune Privilege

Hardcover

Series: Birkhäuser Advances in Infectious Diseases

Medical ReferenceBiology

ISBN10: 303480444X
ISBN13: 9783034804448
Publisher: Springer Nature
Published: Jul 4 2012
Pages: 156
Weight: 0.80
Height: 0.70 Width: 6.30 Depth: 9.20
Language: English

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated immune-privileged sites by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.

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