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Dokladnośc testu Gene Xpert firmy Cepheid
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ISBN10: 6202209526
ISBN13: 9786202209526
Publisher: Wydawnictwo Nasza Wiedza
Published: Sep 11 2025
Pages: 72
Weight: 0.24
Height: 0.17 Width: 6.00 Depth: 9.00
Language: Polish
ISBN13: 9786202209526
Publisher: Wydawnictwo Nasza Wiedza
Published: Sep 11 2025
Pages: 72
Weight: 0.24
Height: 0.17 Width: 6.00 Depth: 9.00
Language: Polish
Gruźliczy wysięk oplucnowy jest częstą przyczyną przyjęcia pacjentów do szpitala Mulago, zwlaszcza wśród pacjentów zakażonych wirusem HIV. Badanie histologiczne i hodowla tkanki oplucnej w kierunku MTB, będące zlotym standardem, wymagają inwazyjnej procedury, która wymaga specjalnych umiejętności i jest czasochlonna. Przetestowaliśmy dokladnośc diagnostyczną testu Gene Xpert firmy Cepheid, specyficznego dla MTB, opartego na PCR i wykorzystującego plyn oplucnowy, w celu uzyskania szybszej, bardziej przyjaznej dla użytkownika, dokladnej i mniej inwazyjnej metody diagnozowania gruźlicy oplucnej w naszych warunkach. Wykazano, że test ten poprawia diagnostykę gruźlicy plucnej, zapewniając dokladnośc w mniej niż 2 godziny. W niewielkich badaniach pilotażowych odnotowano różne poziomy dokladności tego testu w diagnostyce gruźlicy oplucnej. Jednak badanie przeprowadzone w RPA przez Svena i wsp. w 2011 r. wykazalo czulośc na poziomie 25% i swoistośc na poziomie 100% w 20 próbkach pobranych od pacjentów z potwierdzoną gruźlicą oplucnej. Cele: Określenie dokladności testu Gene Xpert przeznaczonego do wykrywania gruźlicy w diagnostyce gruźlicy oplucnej u doroslych pacjentów z podejrzeniem gruźliczego wysięku oplucnowego zglaszających się do oddzialu pulmonologii szpitala Mulago w okresie objętym badaniem.
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