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Sieroepidemiologia della trasmissione trasfusionale di Toxoplasma gondii, CMV e
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ISBN10: 620887369X
ISBN13: 9786208873691
Publisher: Edizioni Sapienza
Published: Jul 11 2025
Pages: 56
Weight: 0.19
Height: 0.13 Width: 6.00 Depth: 9.00
Language: Italian
ISBN13: 9786208873691
Publisher: Edizioni Sapienza
Published: Jul 11 2025
Pages: 56
Weight: 0.19
Height: 0.13 Width: 6.00 Depth: 9.00
Language: Italian
La sieroepidemiologia delle infezioni trasmesse con la trasfusione, come Toxoplasma gondii, citomegalovirus (CMV) e parvovirus B19, tra i donatori di sangue sani in India sottolinea una significativa preoccupazione per la salute pubblica, in particolare per gli individui immunocompromessi, i neonati e le donne in gravidanza. Studi condotti in varie regioni dell'India rivelano che la sieroprevalenza degli anticorpi IgG di T. gondii tra i donatori di sangue varia dal 20% al 25% circa, indicando un'esposizione passata, mentre una percentuale minore mostra positività alle IgM, suggerendo infezioni recenti. Il CMV presenta una sieroprevalenza notevolmente elevata tra i donatori di sangue indiani, con tassi di positività IgG riportati tra il 90% e il 97%, che riflettono una diffusa esposizione precedente, mentre la positività IgM rimane bassa, indicando un minor numero di infezioni recenti. Gli studi di sieroprevalenza del Parvovirus B19 indicano che gli anticorpi IgG sono presenti in circa il 27-40% dei donatori, a testimonianza di una precedente esposizione, mentre gli anticorpi IgM sono stati rilevati in circa l'1,4%-7,5% dei donatori, a indicare infezioni attuali o recenti. Questi risultati evidenziano il rischio potenziale di infezioni trasmesse per via trasfusionale e sottolineano l'importanza di attuare strategie di screening mirate.
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