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Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond

Mechanisms of Lymphocyte Activation and Immune Regulation VIII: Autoimmunity 2000 and Beyond

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 490

Medical ReferenceBiologyBotany & Horticulture

ISBN10: 0306465701
ISBN13: 9780306465703
Publisher: Springer Nature
Published: Jul 31 2001
Pages: 136
Weight: 0.88
Height: 0.44 Width: 6.14 Depth: 9.21
Language: English
Advances in biochemistry, cell biology, genome-wide mutagenesis - coupled with molecular technology, including gene microarray and transgenic and knock-out animals - have been instrumental in understanding the cellular processes and molecular pathways of self-tolerance and autoimmune diseases. The molecular definition of these pathways and processes has led to novel treatments for certain auto-immune diseases that are based on the pathogenesis of diseases rather than on broad-spectrum immunosuppression. This book reviews many of these current developments and proposes future novel approaches for understanding the pathogenesis of auto-immune diseases and designing novel therapy. This book covers three major areas of auto-immunity: the basic mechanisms of immunological tolerance, pathogenesis of auto-immune diseases, and some novel therapies.
This book should be useful for immunologists, molecular biologists, rheumatologists, and clinical scientists.

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