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Transformation of Human Epithelial Cells (1992): Molecular and Oncogenetic Mechanisms

Transformation of Human Epithelial Cells (1992): Molecular and Oncogenetic Mechanisms

Hardcover

Series: CRC Press Revivals

Medical ReferenceBiology

ISBN10: 1138105031
ISBN13: 9781138105034
Publisher: CRC Press
Published: Oct 2 2017
Pages: 326
Weight: 1.39
Height: 0.75 Width: 6.14 Depth: 9.21
Language: English
This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading.

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