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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Acute generalized exanthematous pustulosis

Acute generalized exanthematous pustulosis

Zaouak, Anissa
Hammami, Houda
Fenniche, Samy

Paperback

Medical Reference

ISBN10: 6208041953
ISBN13: 9786208041953
Publisher: Our Knowledge Publishing
Published: Sep 3 2024
Pages: 52
Weight: 0.20
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Acute generalized exanthematous pustulosis (AGEP) is a rare form of toxidermia, one of the severe cutaneous adverse drug reactions (SCAR). It is a febrile, erythematous, putular cutaneous reaction, most often caused by drugs. It may also be due to a viral infection (enterovirus: coxsackie, echovirus or cytomegalovirus), a toxic substance (mercury) or a food allergen. All ages are concerned. The drugs most often responsible are antibiotics such as beta-lactams and pristinamycin. PEAG is a model of delayed drug hypersensitivity mediated by CD8 T lymphocytes. The onset of this toxidermia is short, ranging from a few hours to a few days. Diagnosis of this dermatosis is based on clinical and para-clinical criteria. These criteria were validated by a score, established in 2001 by the European SCAR study group (EuroSCAR).Clinically, PEAG manifests as a bright red, sometimes scarlatiniform, edematous erythema, undertaking the trunk, limbs, and more particularly the axillary and inguinal folds.

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