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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Anti-falsification and anti-hemolytic effects of Spirulina Platensis

Anti-falsification and anti-hemolytic effects of Spirulina Platensis

Pieme, Constant Anatole

Paperback

Medical Reference

ISBN10: 6209272916
ISBN13: 9786209272912
Publisher: Our Knowledge Publishing
Published: Nov 23 2025
Pages: 96
Weight: 0.31
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English
Sickle cell anemia (SCA) is a genetic disease associated with chronic hemolytic anemia. The aim of this study was to evaluate the anti-calciformation and anti-hemolytic activity of aqueous extracts of Spirulina platensis (SP). The maximum percentage of falciformation was 91.44%, while the rate of falciformation inhibition after 2 h 30 by spirulina extract ranged from 15.10% to 66.09%. The rate of inhibition was dose-dependent, and the rate of reversibility of falciformation ranged from 37.54% to 82.34% as a function of time. The extract improved the Fe2+/Fe3+ ratio with high values of 69.78% and 69.78%. Inhibition of hemolytic inducers ranged from 24.26% to 96.67%, depending on the concentration and nature of the inducer. SP extract demonstrated antihemolytic properties on various hemolytic inducers, with inhibition rates ranging from 36% to 96%.Aqueous SP extract showed anti-sickle cell properties, reversibility of sickle cells in a dose-dependent manner, and antihemolytic activity.

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