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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Carcinomatous meningitis of breast origin: What is the prognosis?

Carcinomatous meningitis of breast origin: What is the prognosis?

Boudaouara, Ons

Paperback

Medical Reference

ISBN10: 6208940346
ISBN13: 9786208940348
Publisher: Our Knowledge Publishing
Published: Jun 17 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Carcinomatous meningitis (CM) is a rare and late event, complicating around 5 to 8% of breast cancers. At this stage, median survival drops dramatically, rarely exceeding 6 months. These disappointing results have prompted some authors to investigate factors that may influence patient prognosis, in an attempt to stratify prognosis and adapt therapeutic protocols. In this study, we investigated the prognostic impact of certain clinico-pathological and therapeutic factors in a retrospective study of 20 patients with CD of breast origin over a 16-year period between 2005 and 2021. Death attributable to the disease was noted in 19 cases, with an estimated median overall survival of 5 months. The results of our study confirm the positive prognostic value of a high performance status at the time of diagnosis of CD and the administration of adequate systemic treatment. The negative prognostic impact of the presence of brain metastases and the use of a single therapeutic modality was verified in uni and multivariate analysis.

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