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CD34+ a Novel Predictor of Vascular Events in Sickle Cell Disease

CD34+ a Novel Predictor of Vascular Events in Sickle Cell Disease

Paperback

Medical Reference

ISBN10: 6208118336
ISBN13: 9786208118334
Publisher: LAP Lambert Academic Publishing
Published: Sep 30 2024
Pages: 112
Weight: 0.39
Height: 0.27 Width: 6.00 Depth: 9.00
Language: English
Our aim is to evaluate circulating CD34 as a novel predictive marker of occurrence of vascular event in Children with Sickle Cell Disease in their steady state and relate levels to severity of VEs in the following 6 months.Patient and Methods: This study was an exploratory study, conducted at Pediatrics Hematology-Oncology Unit at Ain Shams University Children's Hospital, where 50 children with sickle cell disease were enrolled at their steady state (defined as 2 months free from any Vascular Event prior to the study), aged 6 months - 16 years. Flow cytometry was done for quantification of circulating CD34+ at inclusion and compared to age and sex matched control and patients were followed up for 6 months for vascular events. Results: There is statistically significant higher level of CD34+ among SCD patients compared to age and sex matched control with p value

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Badawi, Rania

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Medical Reference