Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Dental Caries Immunization

Dental Caries Immunization

Ghune, Divya
Patil, Aarti

Paperback

Medical Reference

ISBN10: 6208417635
ISBN13: 9786208417635
Publisher: LAP Lambert Academic Publishing
Published: Dec 19 2024
Pages: 72
Weight: 0.26
Height: 0.17 Width: 6.00 Depth: 9.00
Language: English
Dental caries immunization refers to developing vaccines aimed at preventing dental caries (tooth decay), a chronic disease caused primarily by Streptococcus mutans and other cariogenic bacteria. These bacteria metabolize sugars in the oral cavity, producing acids that demineralize tooth enamel and lead to decay. Dental caries vaccines aim to stimulate the immune system to produce antibodies that neutralize the virulence factors of S. mutans, such as glucosyltransferase enzymes, which are critical for biofilm formation and acid production. Immunization strategies include active vaccines that trigger the body's immune response and passive immunization using preformed antibodies. Although research in this field has shown promise, with several candidate vaccines demonstrating efficacy in preclinical and early clinical studies, challenges such as safety, cost, and ethical considerations remain. The development of an effective dental caries vaccine could significantly reduce the global burden of tooth decay, particularly in underserved populations lacking access to proper dental care.

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