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Epigenetic Alterations in Oncogenesis

Epigenetic Alterations in Oncogenesis

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 754

Medical Reference

ISBN10: 1441999663
ISBN13: 9781441999665
Publisher: Springer Nature
Published: Sep 6 2012
Pages: 348
Weight: 1.40
Height: 1.00 Width: 6.20 Depth: 9.20
Language: English
The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means above genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.

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