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Features and Management of Acute and Chronic Neuro-Covid

Features and Management of Acute and Chronic Neuro-Covid

Hardcover

Medical Reference

ISBN10: 3030867048
ISBN13: 9783030867041
Publisher: Springer Nature
Published: Nov 28 2021
Pages: 158
Weight: 1.00
Height: 0.40 Width: 8.00 Depth: 9.50
Language: English

This book delineates that COVID-19 is a multisystem inflammatory disease and how its pathophysiology can predispose patients to an increased risk of neurological problems. Available data suggest the potential neuroinvasive capacity of the SARS-CoV-2 through direct viral damage and indirect entering the CNS by different routes including the vascular system, the olfactory and trigeminal nerves, the cerebrospinal fluid, and the lymphatic system. Furthermore, the pro-inflammatory cytokine storm and oxidative stress can induce microglial activation and damaging the blood-brain barrier, culminating in widespread neuroinflammatory processes. This acute neurotoxicity is clinically expressed as anosmia, ageusia, headache, nausea and vomiting. Other neurologic manifestations such as acute cerebrovascular diseases, encephalitis-based impaired consciousness, and meningitis are also described.

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Medical Reference