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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Formulation of Film Coated Tablets of Norfloxacin and Tinidazole

Formulation of Film Coated Tablets of Norfloxacin and Tinidazole

Shinde, Anilkumar
More, Harinath

Paperback

Medical Reference

ISBN10: 6139977363
ISBN13: 9786139977369
Publisher: Lap Lambert Academic Pub
Published: Dec 13 2018
Pages: 96
Weight: 0.33
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English
The aim of the present study was development and optimization of an efficacious, pharmaco-economical, palatable and marketable film coated tablet formulation of Norfloxacin-Tinidazole. Bitter taste of both drugs reduces the patient compliance & hence marketability. However it has been shown that film coating technology economical & useful in masking the taste. The core tablets with maximum hardness & minimum disintegration time were selected for film coating. (F-1 & F-07) The optimized formulation F-07 showed hardness, friability, disintegration time and drug release in range 9 kg/cm2, 0.17 0.02%, 27.40 2.1 sec. & 100% release in 30 min. respectively. For all tablet formulation drug release at the end of 30 min was found in the range of 52.78 0.09 to 100.07 0.5 % and from the obtained results, F-07 was selected as an optimized formulation for designing palatable tablet. Therefore it can be concluded that the present work discusses in depth the development and optimization of an efficacious, pharmaco-economical, palatable and marketable tablet formulation of Norfloxacin and Tinidazole.

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