Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Mitotic Figures in Epithelial Dysplasia and Squamous Cell Carcinoma

Mitotic Figures in Epithelial Dysplasia and Squamous Cell Carcinoma

Bhardwaj, Alka

Paperback

Medical Reference

ISBN10: 6208172195
ISBN13: 9786208172190
Publisher: LAP Lambert Academic Publishing
Published: Oct 9 2024
Pages: 52
Weight: 0.20
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
The oral epithelial dysplastic lesion also called as a pre-cancer lesion is among the most intricate topics of head and neck pathology. The concept of a stepwise development of cancer in the oral mucosa, i.e., the initial presence of a precursor (pre-malignant/precancerous) lesion subsequently developing into cancer is well established. The presence of epithelial dysplasia may be even more important in predicting malignant development than the clinical characteristics. Defects of mitosis results in various nuclear abnormalities, namely, micronuclei, binucleation, broken egg appearance, pyknotic nuclei and increased number of and / or abnormal mitotic figures These abnormal mitotic figures are commonly seen in oral epithelial dysplasia and squamous cell carcinoma. Increased numbers of and / or abnormal mitotic figures are important criteria that carry increased weightage in the grading of dysplasias and scc.A properly standardized histochemical stain and precise use of morphological criteria for identification of mitotic figures helps in proper idendification.

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