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612-822-4611
Neonatal Auto-Immune Thrombocytopenia

Neonatal Auto-Immune Thrombocytopenia

Paperback

Medical Reference

ISBN10: 6208920388
ISBN13: 9786208920388
Publisher: Our Knowledge Publishing
Published: May 31 2025
Pages: 56
Weight: 0.19
Height: 0.13 Width: 6.00 Depth: 9.00
Language: English
Neonatal immunologic thrombocytopenia (NITT) is a serious complication in neonates of women with immunologic thrombocytopenic purpura (ITP). Previous pregnancy with TINN or splenectomy-refractory ITP in the mother have been described as associated with the occurrence of TINN. We have reported five cases in which ITP was already diagnosed in two parturients, and neonatal thrombocytopenia was diagnostic in the remaining three. Prenatal treatment of thrombocytopenia with corticosteroids and/or Ig infusion was initiated in three women, with a favorable outcome in only one case. Caesarean delivery was used in 4 cases, and no post-partum bleeding was observed. For newborns, a clinical hemorrhagic syndrome was found in two cases, and treatment was based on Ig injections and platelet transfusions for all newborns, with a good outcome in 04 cases. Prenatal treatment was based on corticosteroid therapy and/or immunoglobulin infusions to maintain a platelet count above 50 G/L before delivery.

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Frikha, Imen

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Medical Reference