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Nmda Antagonists as Potential Analgesic Drugs

Nmda Antagonists as Potential Analgesic Drugs

Hardcover

Series: Progress in Inflammation Research

Medical Reference

ISBN10: 3764360119
ISBN13: 9783764360115
Publisher: Springer Nature
Published: Jan 1 2002
Pages: 194
Weight: 1.04
Height: 0.50 Width: 6.14 Depth: 9.21
Language: English
There is now considerable preclinical evidence that glutamate acting via the NMDA receptor is involved in the transmission of nociceptive information and in the triggering mechanisms for hyperalgesia and allodynia. This evidence allows rational development of a new class of analgesic drugs that act as antagonists of the NMDA receptor, supported by emerging evidence with existing excitatory amino acid antagonists. L

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