Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Osteoimmunology in Periodontal Disease

Osteoimmunology in Periodontal Disease

S, Divya
Burhan K. B., Basim
P. R., Arunima

Paperback

Medical Reference

ISBN10: 6208063515
ISBN13: 9786208063511
Publisher: LAP Lambert Academic Publishing
Published: Sep 6 2024
Pages: 96
Weight: 0.33
Height: 0.23 Width: 6.00 Depth: 9.00
Language: English
Shifts in the composition and quantity of microbes within dental plaque biofilms can drive a local proinflammatory immune response state in the epithelial and gingival barrier connective tissues. Infiltrating proinflammatory immune cells within the inflamed connective tissue secrete local factors that induce paracrine signaling to subjacent bone cells. Sustained chronic inflammation disrupts coupled osteoclast-osteoblast actions, which ultimately result in alveolar bone destruction.The field of osteoimmunology has emerged in response to the range of evidences demonstrating the close interrelationship between the immune system and bone metabolism.. Molecular insight into the field of osteoimmunology can lead to novel approaches for the prevention and treatment of diverse inflammatory conditions. As shown by the clinical benefits conferred by anti-tumor necrosis factor (TNF)-α and anti-interleukin (IL)-6 treatment in RA, osteoimmunological insight is now of obvious importance in clinical applications. Translating these knowledges to periodontal disease in future may benefit the treatment of periodontitis.

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