Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Overview of Malaria Infection and Haematological Indices in Africa

Overview of Malaria Infection and Haematological Indices in Africa

Antwi-Baffour, Samuel

Paperback

Medical Reference

ISBN10: 6206772179
ISBN13: 9786206772170
Publisher: Scholars' Press
Published: Oct 22 2024
Pages: 84
Weight: 0.30
Height: 0.20 Width: 6.00 Depth: 9.00
Language: English
Malaria, a severe parasitic disease transmitted by Anopheles mosquitoes, is caused by various Plasmodium species, with P. falciparum and P. vivax posing the greatest threat. While most infections are uncomplicated, a small percentage progresses to severe malaria, characterized by disruptions in immune cell profiles and increased cytokine levels. Severe P. falciparum malaria is associated with elevated plasma cytokines, T cell lymphopenia, and impaired T cell function. Treatment aims to restore immune cell balance, particularly CD3+, CD4+, and CD8+ cells. Protective immunity involves CD8+ T cells and cytokines like IFN-γ and TNF, while CD4+ T cells combat erythrocytic parasites through cytokine secretion and macrophage activation. Regulatory T cells also play a role, highlighting the importance of cytokine balance in malaria. Additionally, factors like antigen affinity influence T helper lymphocyte differentiation, affecting immune responses to the disease.

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