Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Pro- Inflammatory Markers as a Risk Factor in Chronic Periodontitis

Pro- Inflammatory Markers as a Risk Factor in Chronic Periodontitis

Bansal, Arunima
Anand Arora, Sachit
A. Das, Jeevika

Paperback

Medical Reference

ISBN10: 6208447178
ISBN13: 9786208447175
Publisher: LAP Lambert Academic Publishing
Published: May 22 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
Chronic Periodontitis is a complex inflammatory disease influenced by both microbial and host-related factors. Among the most significant host-derived contributors are Pro-inflammatory markers such as interleukin-1β (IL-1β), tumor necrosis factor-alpha (TNF-α), prostaglandin E2 (PGE2) and Macrophage Inflammatory Protein(MIP-1α). These biomarkers play a critical role in mediating the inflammatory response to periodontal pathogens, leading to the destruction of connective tissue and alveolar bone. Elevated levels of these markers in gingival crevicular fluid, saliva, or serum have been consistently associated with increased disease severity and progression. Their presence reflects an exaggerated host response, making them valuable indicators of active periodontal destruction. As such, pro-inflammatory markers are not only involved in the pathogenesis of chronic periodontitis but they also serve as important risk factors for its onset and advancement.

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