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Genotype - Proteotype - Phenotype Relationships in Neurodegenerative Diseases
Paperback
Series: Research and Perspectives in Alzheimer's Disease
ISBN13: 9783642063954
Publisher: Springer
Published: Oct 19 2010
Pages: 166
Weight: 0.58
Height: 0.39 Width: 6.14 Depth: 9.21
Language: English
Recent advances in understanding the role of protein dysmetabolism in neurodegeneration was the theme of the Fondation IPSEN meeting addressing Genotype-Proteotype-Phenotype relationships. Experts from international laboratories contributed to the current volume to produce a comprehensive overview of the role of protein misfolding in neurodegeneration. Links between genotype and protein characteristics and between proteotype and clinical phenomenology were discussed across diseases categories. Progress in understanding the role of abnormalities of protein metabolism may lead to the identification of biological markers relevant to disease monitoring and to the development of new therapeutic agents capable of modifying and ameliorating basic neurodegenerative mechanisms.
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