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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Association of Single Nucleotide Polymorphism of TLR-2 and IL-33 Gene

Association of Single Nucleotide Polymorphism of TLR-2 and IL-33 Gene

Fouaad Abaas, Hind

Paperback

Biology

ISBN10: 6207996658
ISBN13: 9786207996650
Publisher: LAP Lambert Academic Publishing
Published: Feb 17 2025
Pages: 136
Weight: 0.42
Height: 0.32 Width: 6.00 Depth: 9.00
Language: English
Rheumatoid arthritis (RA) represents the chronic inflammatory disease prototype;it is characterized by synovial membrane inflammation, cartilage destruction, boneerosion, joint deformity and functional disability of the affected individual.Molecular and Immunological study was performed to determine the influences ofgenetic variants of the IL-33 and TLR-2 genes on IL-33 level and TLR-2 level inRA patients as well as determined the genotypes and alleles associated with theincidence of RA disease.The case study included 35RA patientssuffering from streptococcus pyogenesinfection (4 male and 31female) attending the to rheumatoid arithritis diseasecenter at Al- Sadder Medical City in AL- Najaf Provenancein the period extendingfrom November 2018 until end of January 2019. With ages ranged from30 to 69years old. The control groups included 15 healthy persons (5 male and 10 female)with the same ages and sex of the patients were randomly selected from thehospitals and the local community. After the demographic and clinical data were-collected from the patients, the sera were used to determine total serum IL-33, TLR-2 levels by Enzyme-linked immunosorbent assay, Anti-streptolysinO(ASO) test.

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