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Metabolisches Syndrom
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ISBN10: 6208986982
ISBN13: 9786208986988
Publisher: Verlag Unser Wissen
Published: Jun 20 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: German
ISBN13: 9786208986988
Publisher: Verlag Unser Wissen
Published: Jun 20 2025
Pages: 64
Weight: 0.22
Height: 0.15 Width: 6.00 Depth: 9.00
Language: German
Das metabolische Syndrom ist eine Gruppe von Erkrankungen, die das Risiko von Herzerkrankungen, Schlaganfällen und Diabetes erhöhen. Es ist gekennzeichnet durch abdominale Adipositas, Bluthochdruck, Hyperglykämie und Dyslipidämie und erfordert mindestens drei Diagnosekriterien: einen Taillenumfang von >102cm bei Männern oder >88cm bei Frauen, Triglyceride >=1,7mmol/L, einen niedrigen HDL-Wert, Bluthochdruck (>=130/85mmHg) und einen Nüchternblutzuckerspiegel >=1.1g/L. Zu den Faktoren, die zu seiner Entstehung beitragen, gehören Fettleibigkeit, Bewegungsmangel, Genetik, Alter, ethnische Zugehörigkeit, hormonelle Veränderungen, Ernährung, Rauchen und Alkoholkonsum. Die Pathophysiologie ist komplex und beinhaltet eine Insulinresistenz (IR) in Verbindung mit überschüssigem viszeralem Fett, das entzündungsfördernde Zytokine und freie Fettsäuren freisetzt, die IR und Entzündungen verschärfen. IR stört auch den Fettstoffwechsel, was zu einer Dyslipidämie führt, und kann die Endothelfunktion beeinträchtigen, wodurch die Atherogenese begünstigt wird. Dies erhöht das Risiko von koronarer Herzkrankheit, Schlaganfall, peripherer arterieller Verschlusskrankheit, Herzinsuffizienz und Nierenerkrankungen.
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