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SÃndrome metabólica
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ISBN10: 6208987032
ISBN13: 9786208987039
Publisher: Edicoes Nosso Conhecimento
Published: Jun 20 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: Portuguese
ISBN13: 9786208987039
Publisher: Edicoes Nosso Conhecimento
Published: Jun 20 2025
Pages: 60
Weight: 0.21
Height: 0.14 Width: 6.00 Depth: 9.00
Language: Portuguese
A sÃndrome metabólica é um grupo de condições que aumentam o risco de doença cardÃaca, acidente vascular cerebral e diabetes. Caracteriza-se por obesidade abdominal, hipertensão, hiperglicemia e dislipidemia, exigindo pelo menos três critérios de diagnóstico: perÃmetro da cintura >102cm nos homens ou >88cm nas mulheres, triglicéridos >=1,7mmol/L, HDL baixo, hipertensão (>=130/85mmHg) e glicemia em jejum >=1,1g/L. Os factores que contribuem para o seu desenvolvimento incluem a obesidade, o sedentarismo, a genética, a idade, a etnia, as alterações hormonais, a dieta, o tabagismo e o consumo de álcool. Tem uma fisiopatologia complexa que envolve a resistência à insulina (RI) associada ao excesso de gordura visceral, que liberta citocinas pró-inflamatórias e ácidos gordos livres, exacerbando a RI e a inflamação. A IR também perturba o metabolismo dos lÃpidos, levando à dislipidemia, e pode prejudicar a função endotelial, promovendo a aterogénese. Esta situação aumenta o risco de doença coronária, acidente vascular cerebral, doença arterial periférica, insuficiência cardÃaca e doença renal.
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