Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Vitamin D & peripheral arterial disease

Vitamin D & peripheral arterial disease

Bouragba, Imane
Diaf, Mustapha

Paperback

Biology

ISBN10: 6208716071
ISBN13: 9786208716073
Publisher: Our Knowledge Publishing
Published: Mar 7 2025
Pages: 52
Weight: 0.18
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
This book explores peripheral arterial disease (PAD), resulting from atherosclerosis. This process is caused by the accumulation of altered lipids, notably oxidized LDL, in the arteries. PAD is an inflammatory condition affecting peripheral arteries, with an alarming prevalence, affecting 10-26% of the world's population. Chronic inflammation is a key factor in the initiation and progression of atherosclerosis. Pro-inflammatory cytokines contribute to endothelial dysfunction and the accumulation of inflammatory cells, increasing the risk of complications. The book highlights the role of vitamin D in the pathophysiology of PAD. It regulates nitric oxide (NO) levels and reduces the expression of pro-inflammatory cytokines, limiting inflammation and lipid accumulation in atherosclerotic plaques. In addition, vitamin D receptor (VDR) polymorphism can influence vitamin D sensitivity. Vitamin D deficiency is common, even in healthy individuals, underlining the importance of this nutrient for the prevention of vascular disease.

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